The innovative TEM-AGMD technology combines membrane distillation with thermoelectric modules, allowing for the elimination of numerous components found in traditional MD systems. This compact and energy-efficient approach enables decentralized water treatment and desalination with excellent salt rejection and minimal power consumption. Optimal performance is achieved by increasing the number of thermoelectric modules, implementing multi-stage membrane distillation, and intensifying the feed flow rate. The TEM-AGMD technology shows great potential for developing hybrid systems for decentralized water treatment and desalination, achieving a minimal specific energy consumption of 962 kWh/mÂł.